Senior Principal Scientist, Medicinal Chemistry @ Pfizer

Job Information

Job Description:

KEY RESPONSIBILITIES

Drive a strong scientific agenda and the application of expert data analysis and contemporary design tools to drive effective target design and prioritization within a portfolio of projects
Contribute to medicinal chemistry strategy and devising hit identification strategies to move projects through the Hit-to-Lead phase with scientific excellence, efficiency, and speed
Play a key role in progressing projects through the Lead Optimization phase in partnership with enabling functions within Medicine Design, including Structural Biology; Chemical Biology; Primary Pharmacology; and Pharmacokinetics & Drug Metabolism, to ensure the delivery of small-molecule/synthetic drug candidates with scientific excellence, efficiency, and speed
Partnership with enabling functions across Pfizer, including Drug Safety, formulations, and process chemistry to drive project advancement to the clinic.
Contribute to the identification of new small-molecule projects and their entry to the portfolio through collaborations with disease area biologists
Play a role in enhancing the external reputation of Pfizer’s Medicinal Chemistry, Molecular Design, and synthetic Drug Discovery capabilities through publications and presentations at leading conferences
Promote and evaluate the application of novel approaches, methods, and modalities to the drug discovery process
Work with local Medicine Design leadership to put an active program of self-development in medicinal chemistry skills in place

BASIC QUALIFICATIONS

Ph.D. degree in Organic/Medicinal Chemistry or related area of science
Minimum 5 years related medicinal chemistry experience in the biopharmaceutical industry
Track record of delivering high impact contributions to medicinal chemistry projects
Expert working knowledge of the key medicinal chemistry concepts and design tools required for pharmaceutical drug discovery
Consistent record of peer-reviewed publications from scientific work to date

PREFERRED QUALIFICATIONS

Examples of high-impact publications in the field of Medicinal Chemistry/Drug Discovery
Experience leading matrix teams of scientists to deliver defined project objectives

Benefits:
Experience Level: Senior
Work From: Onsite